Resolving the daratumumab interference with blood compatibility testing
نویسندگان
چکیده
منابع مشابه
Interference of daratumumab with pretransfusion testing, mimicking a high-titer, low avidity like antibody
Daratumumab is a monoclonal immunoglobulin against CD38 and has been approved for treating patients with refractory multiple myeloma. The presence of daratumumab in the sera can interfere with pretransfusion testing due to the weakly expression of CD38 on red cells. The reactivity could be mistaken as autoantibody (if autocontrol is positive) or alloantibody (if autocontrol is negative). We pre...
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ژورنال
عنوان ژورنال: Transfusion
سال: 2015
ISSN: 0041-1132,1537-2995
DOI: 10.1111/trf.13069